Global demand for IT resources continues to accelerate and push the envelope of data center design and build speed, cost, sustainability, demand for jobsite resources and need for adaptability as new generations of IT equipment are deployed.  Innovation in data center design, construction and life cycle adaptability are an imperative to reduce impact on energy grid, carbon footprint, and water usage.  Transitioning from traditional hyperscale IT Equipment (ITE) infrastructure to sustainable, adaptable data center ecosystems requires advancement of digitization for data center design and delivery, dynamic integration of liquid cooled ITE with air cooled ITE, and optimization of energy consumption (heat reuse).  This panel will look at guidance and best practices integrating reference designs with high level Building Information Model (BIM) content, adaptable deployment of liquid cooled ITE, circularity in design, elimination of water use and alignment of waste heat with reuse applications.